![]() The sensory areas of the brain that allow us to engage with the external world are very much separated from the reflective areas of the brain that allow us to engage with ourselves. In our day-to-day lives, we have a very good demarcation of what happens inside us versus what happens outside. What you have as a result is a more integrated connectivity in the brain. The hierarchy is dysregulated, flattens out. They start to work in synchrony with the rest of the brain. What we see with DMT (specifically N,N-Dimethyltryptamine) is that the systems that generate complex behaviors and tasks stop working in this specialized fashion. You have different networks and systems that crystallize as we grow older. The brain usually functions in this modular, organized, hierarchical way. The way in which we construct meaning, essentially. In our latest study we looked at brain scans using fMRI and EEG, and found that this feeling of immersion appears to be underpinned by a dysregulation of the systems in the human brain-in the prefrontal cortex, in the temporal cortices-involved in planning, decision making, and semantics. In that DMT experience, they sometimes encounter beings. The DMT experience is one in which people report going into a different dimension, an alternate reality that feels convincingly real, even more real than this everyday reality. What happens to my brain on the psychedelic DMT? ![]() ![]() One question for Christopher Timmermann, a cognitive neuroscientist at the Centre for Psychedelic Research at Imperial College London, where he leads the DMT Research Group and focuses on the nature of consciousness.
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